What is stomach cancer?
The body is made up of many types of cells. Normally, cells grow, divide and die. Sometimes, cells mutate (change) and begin to grow and divide more quickly than normal cells. Rather than dying, these abnormal cells clump together to form tumors. If these tumors are cancerous (also called "malignant"), they can invade and kill your body's healthy tissues. From these tumors, cancer cells can metastasize (spread) and form new tumors in other parts of the body. By contrast, noncancerous tumors (also called "benign") do not spread to other parts of the body.
Stomach cancer (also called “gastric cancer”) is the growth of cancer cells in the lining and wall of the stomach.
Who is at risk of getting stomach cancer?
Your chances of getting stomach cancer are higher if you have had a stomach infection caused by bacteria called Helicobacter pylori. You are also more likely to get stomach cancer if you:
1.Are a man
2.Are older than 50 years of age
3.Have several close relatives who have had stomach cancer
4.Smoke cigarettes
5.Abuse alcohol
6.Eat a lot of pickled or salty foods
7.Are an African American, Hispanic American, Asian American or Pacific Islander
Can I prevent stomach cancer?
There is no way to prevent stomach cancer. However, you can help reduce your risk of getting stomach cancer by not drinking a lot of alcohol or smoking. Also, eat a diet high in fresh fruits and vegetables, and vitamin C. Vitamin C is found in foods such as oranges, grapefruit and broccoli.
What are the symptoms of stomach cancer?
Sometimes cancer can grow in the stomach for a long time before it causes symptoms. In the early stages, stomach cancer can cause the following symptoms:
1.Indigestion, stomach discomfort or heartburn
2.Nausea or loss of appetite
3.Feeling tired
When the cancer is larger, it can cause the following symptoms:
1.Blood in your stool
2.A bloated feeling after eating
3.Vomiting
4.Unexplained weight loss
5.Stomach pain
Many of these symptoms can be caused by conditions other than cancer. However, if you have any of these problems and they don’t go away, talk with your doctor. The earlier stomach cancer is found, the better the chances are that it can be cured.
How can my doctor tell if I have stomach cancer?
If your doctor suspects that you might have stomach cancer, he or she will look at your medical history and do a complete physical exam. Your doctor may want you to get an x-ray test of your stomach. For this test, you drink a liquid containing barium. Barium is a chalky substance that coats the lining of your stomach. This makes it easier for doctors to see on the x-ray.
Your doctor might use endoscopy (say: "in-dos-ko-pee") to try to see the tumor. For this exam, a thin, lighted tube is put into your mouth and passed down to your stomach. Your doctor may give you medicine before the test so that you feel no pain.
During endoscopy, your doctor might take a small piece of your stomach to check for cancer cells. This is called a biopsy sample. The sample is then sent to a lab where it is looked at under a microscope.
How is stomach cancer treated?
Treatment for stomach cancer may include surgery, chemotherapy or radiation therapy, or a combination of these treatments. The choice of treatment depends on whether the cancer is just in the stomach or if it has spread to other places in the body. A person’s age and overall health will also affect the choice of treatment.
Wednesday, January 23, 2008
Stomach cancer
ULCERS
What is an ulcer?
Ulcers are sores on the lining of your digestive tract. Your digestive tract consists of the esophagus, stomach, duodenum (the first part of the intestines) and intestines. Most ulcers are located in the duodenum. These ulcers are called duodenal ulcers. Ulcers located in the stomach are called gastric ulcers. Ulcers in the esophagus are called esophageal ulcers.
What causes ulcers?
A type of bacteria called Helicobacter pylori (H. pylori) causes many ulcers. Acid and other juices made by the stomach can contribute to ulcers by burning the lining of your digestive tract. This can happen if your body makes too much acid or if the lining of your digestive tract is damaged in some way. Physical or emotional stress may not necessarily cause an ulcer, but it can aggravate an ulcer if you have one.Ulcers can also be caused by anti-inflammatory medicines. Although most people take these medicines without problems, long-term use may damage the stomach lining and cause ulcers. Anti-inflammatory drugs include aspirin, ibuprofen (one brand name: Motrin), naproxen (brand name: Aleve), ketoprofen (brand names: Actron, Orudis KT) and some prescription drugs for arthritis.
Possible signs of an ulcer
1.Feel better when you eat or drink and then worse 1 or 2 hours later (duodenal ulcer)
2.Feel worse when you eat or drink (gastric ulcer)
3.Stomach pain that wakes you up at night
4.Feel full fast
5.Heavy feeling, bloating, burning or dull pain in your stomach
6.Vomiting
7.Unexpected weight loss
How can ulcers be treated?
One way to treat ulcers is to get rid of the H. pylori bacteria. Treatment may also be aimed at lowering the amount of acid that your stomach makes, neutralizing the acid and protecting the injured area so it can heal. It's also very important to stop doing things, such as smoking and drinking alcohol, that damage the lining of your digestive tract.
What is triple therapy?
Triple therapy is a treatment to eliminate H. pylori. It is a combination of 2 antibiotics and bismuth subsalicylate (one brand name: Pepto-Bismol). Other combinations may also be effective. This treatment may be used with medicine that reduces the amount of acid your stomach makes.
What about other medicines?
Several other medicines can be used to help treat ulcers. Two types of medicines (H2 blockers and proton pump inhibitors) reduce the amount of acid that your stomach makes. They usually help people start to feel better within 3 days.Antacids neutralize acid that the stomach makes. A medicine called sucralfate (brand name: Carafate) coats the ulcer to protect it from the acid so it has time to heal.Another medicine, misoprostol (brand name: Cytotec), reduces the amount of acid and protects the lining of the stomach. It is usually used to prevent gastric ulcers in people who need to take anti-inflammatory drugs and who have had stomach irritation or ulcers in the past.
How long will I have to take medicine?
Treatment to get rid of H. pylori usually takes about 2 to 3 weeks. Your doctor may want you to take medicine that lowers the stomach acid for up to 8 weeks. Most ulcers heal within this time.If your symptoms come back after you stop taking medicine, your doctor may want you to take a different medicine or take a low dose of medicine even when you're not having symptoms to keep the ulcer from coming back.
Tips on healing your ulcer
1.Don't smoke.
2.Avoid anti-inflammatory drugs such as aspirin and ibuprofen.
3.Avoid caffeine and alcohol (or have them only in small amounts and on a full stomach).
4.Avoid spicy foods if they cause heartburn.
Does what I eat affect my ulcer?
It may. But this isn't true for everyone. Certain foods and drinks may be more likely to make your pain worse. These include both regular and decaffeinated coffee, tea, chocolate, meat extracts, alcohol, black pepper, chili powder, mustard seed and nutmeg. You may want to avoid these things if they bother you. But keep your diet balanced. Try eating small, frequent meals when you're having pain.
Warning signs that your ulcer is getting worse
1.You vomit blood.
2.You vomit food eaten hours or days before.
3.You feel cold or clammy.
4.You feel unusually weak or dizzy.
5.You have blood in your stools (blood may make your stools look black or like tar).
6.You have ongoing nausea or repeated vomiting.
7.You have sudden, severe pain.
8.You keep losing weight.
9.Your pain doesn't go away when you take your medicine.
10.Your pain reaches to your back.
Posted by TimeSharing at 3:38 PM
Labels: Genral diseases
Monday, December 31, 2007
IRREGULAR MENSTRUAL CYCLE
We hear a lot about the menstrual "cycle," which can make it sound as though it happens like clockwork. And we say that a woman who gets her period every 4 weeks is "regular," as though there's something abnormal about women who don't. In fact, most women don't get their periods in exactly the same number of days after the last one.
The Menstrual Cycle
Most girls get their first period between the ages of 10 and 16. This is known as menarche (pronounced: meh-nar-kee).
Doctors often talk about a girl's monthly cycle — the number of days from the start of her period to the start of the next one — in terms of a 28-day cycle. But 28 is just an average figure that doctors use. Women's cycle lengths vary — some have a 24-day cycle, some have a 34-day cycle. And a girl may notice that her cycles are different lengths each month — especially for the few years after she first starts getting her period.
The first day a girl's period comes is Day 1 of her cycle. Around Day 5, her pituitary gland tells her ovaries to start preparing one of the eggs they contain for release. One egg will mature completely. At the same time, the lining of the uterus becomes thick to prepare a nesting place for a fertilized egg in the event that the girl becomes pregnant.
On or about Day 14 of a 28-day cycle, the egg breaks loose (this is called document. The egg makes its way through the fallopian tube into the uterus. If the egg hasn't been fertilized by sperm, it starts to fall apart. About 2 weeks later, the lining and egg leave a girl's body as her period and the whole thing starts all over again — that's why we use the word "cycle."
All this sounds very neat and orderly. But a girl's body may not follow this schedule exactly. It's not unusual, especially in the first 2 years after menarche, to skip periods or to have an irregular menstrual cycle. Illness, rapid weight change, or stress can also make things more unpredictable because the part of the brain that regulates periods is influenced by events like these.
SYMPTOMS
Physical Signs:
1.Irregular Periods (changes in frequency, duration, skipped periods, etc.)
2.Infertility
3.Hot Flashes and Night Sweats
4.Vaginal Dryness
5.Bladder Control Problems
6.Insomnia/Disrupted Sleep
7.Palpitations
8.Weight Gain (especially around your waist and abdomen)
9.Skin Changes (dryness, thinning look)
10.Headaches
11.Breast Tenderness
12.Gastrointestinal Distress and Nausea.
13.Tingling or Itchy Skin.
14."Buzzing" in your head, Electric Shock Sensation
15.Bloating
16.Dizziness/Lightheadedness
17.Sore Joints/Muscles
18.Hair Loss or Thinning
19.Increase in Facial Hair
20.Changes in Body Odor
21.Dry Mouth and Other Oral Symptoms
Emotional Signs:
1.Irritability
2.Mood Swings
3.Lowered Libido
4.Anxiety
5."Brain Fog" -- difficulty concentrating, confusion
6.Memory Lapses
7.Extreme Fatigue/Low Energy Levels
8.Confusion/Lack of Concentration
9.Feeling Emotionally Detached
WHY YOU GET THESE SYMPTOMS....AND WHAT YOU CAN DO ABOUT THEM
Here is a little more on the most common physical symptoms -- and some suggestions on how you can cope with them:
Irregular periods Your periods may come more frequently, every 24 days instead of every 28, or they may come later than they used to. You may have a light period that lasts only a few days, then the next month have very heavy bleeding. Your period may last a shorter amount of time, or go on and on for what feels like an eternity. You may skip a month, then go back to normal for several months, then skip two periods in a row...
This happens because, in the initial phases of premature menopause, your hormones are erratic -- and your periods are reacting to this instability.
The type of irregularity you experience is a usually a tip-off to what is happening in your body:
Shorter cycles (your period comes more frequently) usually signal that you are producing lower levels of estrogen during your preovulatory stage -- and that your FSH levels are higher than normal. With more FSH to stimulate them, your follicles are developing faster -- which shortens your cycle.
Extremely light periods usually means that you aren't making enough estrogen to build up your uterine lining. It can also be a sign of an anovulatory period.
Extremely heavy bleeding is also often a sign of an anovulatory period, but in this case, estrogen builds up the uterine lining at the same time that you aren't producing enough progesterone (since you haven't ovulated and so created a corpus luteum). Without progesterone to stop it, the uterine lining keeps building up, until the estrogen production finally drops off and the lining is shed.
Skipped/less frequent periods usually happens as your ovaries continue declining and your menstrual cycle starts cycling down. Over time, even extremely high levels of FSH don't produce enough estrogen for eggs to mature and for your uterine lining to thicken. As you get closer to menopause, your menstrual cycle usually lengthens. Periods come less frequently, there's more time between them. Then you may begin skipping periods. And eventually, in the biggest change in your menstrual cycle, you will stop having periods altogether.
Infertility Problems Possibly one of the most upsetting clues that you're in premature menopause is the inability to conceive. You may still be having your period, you may still assume everything is perfectly normal -- but you just can't get pregnant. Or you may be noticing irregular periods and assume there's something else wrong with you and never think it's menopause.
Hot Flashes Most people have heard of hot flashes and know them as the trademark symptom of menopause. About 75 to 85% of American women are estimated to get hot flashes when they're in menopause. And where premature menopause is concerned, hot flashes tend to be even more prevalent. Many studies indicate that if you go through natural menopause before age 52, you have an increased chance of having hot flashes. It's even more common for women who have had their ovaries surgically removed -- about 80 to 90% of these women typically get hot flashes.
Hot flashes usually start with a hot, prickly feeling in the middle of your back. A heat wave then rises to envelop your back, chest, neck, face and scalp. Your skin temperature can rise up to 8 degrees. Often if you touch your skin, it actually feels hot as though you've been out in the sun.Your pulse shoots up and you start sweating as your body tries to cool itself down. Sometimes you get a flush -- your face, neck and chest turn pink or even deep red. And very often, you suddenly shift from feeling incredibly hot and sweaty to feeling very chilled, even shivering. You may also get the nighttime version of hot flashes, night sweats.
How to Cope:The good news about hot flashes is that they can be controlled -- by HRT, and also to varying degrees by herbs, vitamins, natural supplements and other alternative methods, covered in chapters 5 and 6.. But there are other small things you can do to help deal with these so-called "power surges."
1.Try to reduce stress.
2.Watch what you wear -- choose natural fibers, layered and loose-fitting clothing.
3.Exercise.
4.Cut back on caffeine, alcohol and spicy foods.
5.Stay cool at night. Have cold water by your bed ready to drink at the first sign of a sweat. Use cotton sheets and cotton nightclothes (I found men's t-shirts to be the best -- cool and absorbent!). As with your clothing, sleep under layers, so you can kick off extra bed covers when you get out and replace them when the chills start.
6.Splash cold water on your face or wrists when a hot flash starts.
Vaginal Dryness and Atrophy When your estrogen levels drop, your vaginal tissues start drying and become less elastic. Sex becomes uncomfortable, you may be more prone to infections, your vagina is frequently itchy and easily irritated, and, on the emotional side, you may feel older.
Vaginal dryness and vaginal atrophy occur when your estrogen levels drop. Your vagina is usually very elastic, able to easily stretch for sex and childbirth. But as estrogen levels go down, your vaginal walls get thinner and lose some of their elasticity. Your vagina becomes dryer and takes longer to become lubricated. Finally, it may atrophy -- becoming somewhat smaller in width and length. If you experience a sudden drop in estrogen (as you do with surgical menopause), these vaginal symptoms might appear more suddenly than if you go through a natural premature menopause. Either way, though, it's a very unpleasant side effect of going through menopause -- and often very emotionally upsetting when you're in your 20s or 30s.
You may find it takes longer and longer to get sexually aroused. Sexual stimulation that you used to enjoy may become unpleasant. Intercourse can be very uncomfortable, even painful. In a worse case scenario, your vagina may even tear during intercourse. All in all, sex may become less and less pleasurable -- making you feel even worse about being in premature menopause. I remember I began thinking that, at the not-so-ripe age of 38, my days of enjoying sex were over -- and was very glad when I learned that I was wrong.
How to Cope:
When you raise your estrogen levels through HRT, your vaginal tissues generally improve dramatically. In addition to standard estrogen replacement therapy (by pills or patches) you can also use a vaginally-inserted estrogen cream or an estrogen ring specifically designed to help with vaginal dryness and atrophy. But there are other things you can try as well.
1.Have more sex -- it's one of the simplest -- and probably most fun! -- ways of combating vaginal dryness. Regular sex helps prevent vaginal dryness.
2.Use a lubricant to help with the loss of lubrication -- such as Astroglide, Lubrin, or KY Jelly., or a product that enhances vaginal moisture such as Replens.
3.Avoid anything that can irritate or dry your vagina -- including perfumed bath oil or bubble bath and perfumed toilet papers.
4.Also avoid antihistamines and certain decongestants.
5.Vitamin E -- a capsule directly inserted in your vagina -- often helps with lubrication.
Bladder Control Problems
This sign of menopause is connected with vaginal dryness and atrophy -- and, honestly, it sounds much worse than it is. You're not going to suddenly have to start wearing Depends. You may, however, notice that you have to urinate more frequently or with more urgency, or you may have urinary stress incontinence, little leaks when you exert yourself. Again, this is a function of lower-than-normal estrogen levels. Your bladder and urethra are formed from the same tissues as your vagina when you're a developing embryo. So, just like your vagina loses muscular tone and elasticity when estrogen production lags, your lower urinary tract does as well. The lining of your urethra becomes thinner, and the surrounding muscles become weaker. As a result, when you place stress on your bladder -- through coughing, sneezing, laughing, or strenuous exercising, you many release a tiny bit of urine. And it is usually only a tiny amount, so there's no need to imagine a real disaster.
If you're experiencing severe urinary incontinence, though, do see a doctor. A small degree of bladder control difficulty is common in the early stages of menopause, but a greater degree of difficulty can be indicative of another problem -- one that may require drugs or even surgery. If it's mild, however, chances are it's connected with your depleted estrogen. Even so, though, it's probably wise to check with your doctor to be sure there is no other cause. Frequent urination may be a sign of bladder infection or diabetes, for example. All in all, it's a good idea just to be sure that what you're experiencing is just another sign of menopause and not something else.
How to Cope:
Since bladder control problems are often a result of low estrogen levels, taking estrogen generally helps -- and may completely reverse any symptoms. But there are other things you can do:
1.Try Kegel exercises - exercises specially designed to help strengthen the muscles around the vagina and bladder opening. An added bonus: since Kegels help your vaginal as well as your bladder muscles, they also can improve your sex life.
2.Cut back on caffeine and alcohol, since both make you urinate more frequently.
Insomnia/Disrupted Sleep
If you're waking up a lot at night, tossing and turning, and generally suffering with insomnia, it might be connected with menopause. When you begin going through menopause, you may find that your sleep is less and less restful -- when you sleep at all. In the past, doctors believed that interrupted sleep was a consequence of night sweats, but recent studies indicate that you can also have problems with sleep that aren't connected to hot flashes. Typically, the frequency of insomnia doubles from the amount you may have had before you entered premature menopause. And research also indicates that women begin to experience restless sleep as many as five to seven years before entering menopause. Again, though, the problem is recognizing that the insomnia you're suffering from has its roots in changes in your hormone levels.
How to Cope:
As with many of the other symptoms, HRT and alternative therapies often work well. In addition, disturbed sleep patterns often level off after a few years. But, of course, you probably don't want to wait a few years. You may want to try the usual tips for getting better sleep. Among them:
1.Drink herbal tea -- like chamomile tea -- before going to bed.
2.Other herbs -- such as valerian -- are natural sedatives that may help.
3.Avoid caffeine, alcohol and other stimulants (like cigarettes) before bedtime -- and avoid strenuous exercise close to your bedtime.
4.Keep your bedroom cool.
Palpitations It's a frightening sensation -- one that may happen at the same time as a hot flash or by itself: For no obvious reason, your heart suddenly starts pounding, racing faster and faster. You can be sitting calmly, or lying in bed just before going to sleep and it comes out of nowhere. Sometimes it makes you so nervous, it can blow up in to a full-fledged panic attack. And if you don't know that you're going through premature menopause and that palpitations are often a sign of menopause, you can think there's something seriously wrong with you.
But palpitations are another not-so-fun sign of menopause -- and one that many women experience. Do keep in mind though: They may signal something else though -- such as hyperthyroidism or mitral valve prolapse -- so don't automatically write off palpitations as a sign of premature menopause. Talk to your doctor to rule out any other, possibly more serious, conditions.
If you get a clean bill of health, there's a good chance that the palpitations are connected with your premature menopause. This is one of those symptoms, though, that some doctors don't associate with menopause, so don't be surprised if your doctor tells you that it must be stress (that catch-all condition) causing your heart troubles. If you've had palpitations in the past, they may get worse when you begin going through menopause.
How to Cope:
1.The best thing to do is probably the hardest thing to do: Calm down.
2.In general, try to keep stress at a minimum.
3.Try relaxation techniques when palpitations hit -- such as deep breathing, imagery, etc.
4.If you smoke, consider quitting, since that often makes palpitations worse.
5.Limit the amounts of alcohol and caffeine you consume.
Weight GainWeight gain -- specifically a thickening in your middle -- is another sign of changing hormones. While a number of books and doctors claim that menopause has nothing to do with weight gain -- that weight gain occurs in menopausal women because they're older and their metabolism is slowing down -- other studies indicate that hormone levels are tied to weight gain and redistribution of fat.
This makes sense since, when you're going through premature menopause, you're not middle-aged -- so what you're getting isn't middle-aged spread. It's menopause spread, for lack of a better term. According to some studies, this occurs for two reasons: First, your progesterone levels are decreasing -- and progesterone increases your metabolic rate. So with lower progesterone levels, you have a slower metabolic rate. Second, estrogen is produced and stored in fat cells. So as your estrogen levels drop, your body is trying to increase its estrogen by upping its fat cells. Finally, with a drop in female hormones, your body starts mimicking male fat distribution -- an apple shape rather than a pear. In other words, you put more weight on in your abdomen than in the past. This accounts for the mysteriously shrinking waistline.
Weight gain and redistribution of fat is one of those signs of premature menopause that is very easy to overlook. Since it happens over a period of time, you might not notice your body shape changing. But if you haven't changed your eating or exercise habits and you've been noticing a new fatter you -- chances are it's related to your hormones.
How to Cope Yet again, you'll notice a change if you opt for HRT or other natural alternatives. In addition, changes in diet and exercise can help rev up your body's metabolic rate.
Changes in your Skin: Wrinkling and Loss of Muscle Tone
When your estrogen levels drop, your collagen production usually slows down as well. And, as you know from reading all the ads for moisturizers and facial creams, collagen is responsible for keeping our skin toned, fresh-looking, resilient. So when you start running low on collagen, it shows in your skin. It gets thinner, drier, flakier, less youthful-looking.
This is another of those symptoms of menopause that makes you feel older before your time -- and, in this case, it's clear why. You may look a little older than you used to. Worst, this sign often shows up early in menopause. Like bone loss, which occurs rapidly in the first few years of menopause, collagen loss is most rapid at the beginning of menopause as well. According to studies, premature menopause leads to more rapid bone loss than menopause that occurs at the normal age -- so it's possible that premature menopause also leads to more rapid collagen loss. The bottom line is, well, more lines....and before you expected them.
How to Cope
Since this change in your skin occurs because of low estrogen levels, when you increase your estrogen levels (either through HRT or phytoestrogens like soy or flaxseed), you will see a definite improvement. Other than this though, there isn't a lot you can do. Using moisturizers helps somewhat by temporarily plumping up the top layer of skin, but the effect is short-lived. And regardless of advertising claims about "collagen-enriched" creams, and so forth, remember that to really work on your skin, collagen must come from within, not be applied from without.
Headaches During the early stages of menopause, you may find that you're getting more -- and worse -- headaches. This is often caused by your dropping estrogen levels. Many women with regular menstrual cycles get headaches just before their periods or at ovulation. These headaches, sometimes called "menstrual migraines" occur when estrogen levels plunge during the menstrual cycle. So, when your body begins slowing down its production of estrogen due to premature menopause, you may wind up getting one of these hormonally-induced headaches. This also can happen when your progesterone levels are too high in relation to your estrogen levels -- a common hormone scenario for women at the beginning of menopause. Generally, these headaches diminish once your hormone levels stabilize.
How to Cope
If your headaches are caused by low estrogen, it follows that taking estrogen may take care of them. But, if you suffer from migraines, HRT may actually increase your symptoms.
1.Try standard over-the-counter remedies -- anti-inflammatories like aspirin or ibuprofen.
2.Certain herbs -- such as feverfew -- are also supposed to help according to several women. Recent studies indicate that feverfew is effective for migraines and other headaches, however, as with any herbal or medicinal remedy, it is wise to check with a doctor before using. In the case of feverfew, be sure to look for products that guarantee at least 0.2 percent of "parthenolide" (the active ingredient) on their label.
3.If the headaches are crippling, talk to your doctor about taking a prescription anti-migraine medication. If you are getting very bad migraines, your only course of action may be taking prescription drugs that specifically help with these intense headaches. Discuss this with your doctor to see if you could benefit from such medication.
Other Physical Signs You May Notice The following symptoms are less obvious and less common, but still are often signs of premature menopause:
Breast Tenderness -- similar to the feeling you get just before your period, your breasts may feel swollen and tender to the touch. This can last for days or weeks -- and unlike the normal breast tenderness from PMS, getting your period often doesn't help relieve this discomfort.
Gastrointestinal Distress and Nausea -- gas, indigestion, heartburn and a green feeling that comes and goes -- and often seems to have no relation to what you've eaten.
Tingling or Itchy Skin -- this may feel like the "creepy-crawlies" as if bugs were walking all over you, a burning sensation like an insect sting, or just super-sensitivity.
"Buzzing" in your head -- an electrical feeling that zaps through your head, often occurs with hot flashes. You may also feel this shock sensation under your skin.
Bloatedness -- a puffy bloated feeling that seems to come out of nowhere; usually you'll notice bouts of this -- you'll be fine for a while, then bloated, then okay again. Unlike PMS bloating, this bloating often doesn't diminish after a period.
Dizziness/Lightheadedness -- sometimes comes with hot flashes, sometimes comes for no apparent reason. This may happen due to a higher progesterone level in relation to your estrogen level
Sore Joints/Muscles -- similar to flu symptoms or arthritis, this often is connected to estrogen deficiency.
Hair Loss or Thinning -- connected to estrogen deficiency, since the hair follicles need estrogen; some women notice this before any other sign because it is so obvious -- you'll notice hair in your brush, your hair may also get drier and more brittle or notice a thinning or loss of pubic hair.
Increase in Facial Hair -- the flip side to the above, you may notice hair growth on your chin, upper lip, abdomen or chest. This hair is often coarser or darker, as well, and happens when your estrogen levels decrease -- and your male hormones have a greater effect or in reaction to high levels of LH
Changes in Body Odor.
Dry Mouth and Other Oral Symptoms -- caused by drying of the mucous membranes due to low estrogen; can include bitter taste in your mouth and bad breath. You also may notice drying in your eyes and nostrils.